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Optimizing Methods in Microtissue Cultivation 02 Sep 2010: This application note shows that InSphero’s GravityPlus technology (patent pending) enables the generation of various microtissue models using either cancer-derived cells to reconstitute tumor tissues or primary cells to mimic structure and function of diverse organs. INTEGRA Biosciences AG
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Performing Cell Growth Curve Experiments with Different Substances on the Eppendorf epMotion® 5075 LH 21 May 2010: This application note make use of the liquid handling system epMotion® 5075 LH to analyze simultaneously the influence of seven different concentrations of three substances dissolved in three different solvents on the growth of the fibroblast cell line NIH/3T3. Eppendorf
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The Eppendorf Research® plus Pipette Fully Autoclavable, Easy Calibration, Quick– and Simple Maintenance 21 May 2010: This application note demonstrates how modern laboratory quality management requires routine cleaning and maintenance - taking time. The Research plus pipettes are easy to clean and maintain. Hence, routine maintenance can be easily performed by the user, saving valuable time. Eppendorf
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Transformation of Bacteria and Spreading onto 24-well Agar Deepwell Plates with Eppendorf epMotion® 5075 21 May 2010: This application note describes the the use of Eppendorf epMotion® 5075 in the transformation of bacteria with DNA and spreading onto agar deepwell plates. After overnight incubation, positive colonies could be observed. Eppendorf
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The Eppendorf Research® plus Pipette – lightweight, reliable and ergonomic 18 May 2010: This application note demonstrates how ergonomics play a large role in todays laboratories. Attention on pipettes no longer focuses exclusively on precision and accuracy; instead, user-friendly operating features, which reduce strain during pipetting, have moved into the foreground. Therefore, ergonomics plays an important role for the user. Eppendorf
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Recommended Pipetting Techniques: for Optimizing Performance 17 May 2010: This technical note describes recommended techniques for optimizing pipette performance. These guidelines can help to achieve optimal accuracy. VIAFLO an INTEGRA company
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Rapid Sample Transfer Between Differing Labware Formats 17 May 2010: This technical note demonstrates a new generation of adjustable spacing pipettes for simple and rapid sample reformatting. The Voyager Multichannel Pipette can bridge the gap between time consuming single channel transfers and the considerable investment required to purchase an automated multichannel liquid handling system. VIAFLO an INTEGRA company
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Non-Contact Acoustic Liquid Dispensing Systems: New Challenges in Automation and Implementation in the Work Flow 10 May 2010: Agilent Automation Solutions has published a technical poster that describes the integration of true non-contact acoustic liquid dispensing technology within an Agilent BioCel System enabling a new level of high throughput automation in a drug discovery environment. The poster describes the configuration of a fully automated compound management solution for screening and developmental assay plates. Agilent Automation Solutions
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Automation of Multiplexed Cell-Based Assay to Measure Induction of Gene Expression and Activity of Cytochrome P450 Isoform 3A4 08 Apr 2010: This application note demonstrates the automation of a cell-based multiplexed assay to explore how a drug can induce gene expression and inhibit activity of the same isoform, creating a useful tool to measure the stimulatory and inhibitory effects of a drug. Activity and induction of gene expression of CYP3A4 were measured using a luminogenic, cell-membrane permeable 3A4-specific substrate and a luciferin based reporter gene assay. BioTek Instruments, Inc.
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Miniaturizing siRNA Transfection Using Acoustic Droplet Ejection 25 Mar 2010: Large-scale, high-throughput siRNA experiments require a transfer system that can facilitate reliable and reproducible transfections in high-density well-plate formats, as well as effective delivery of the siRNA molecule. This application note demonstrates superior performance of the Echo liquid handler compared to more traditional liquid handling methods for standard, reverse and lipid-free transfection of siRNA molecules into mammalian cells. Labcyte
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